Synthesis of 24 a - Substituted Mi } bemycin against Tetranychus urtieae
نویسنده
چکیده
A series of 24a-substituted milbemycin A, deriyatiyes were synthesized from 24a-hydroxymilbemycin A,, which had been obtained by the microbial oxidation of milbemycin A,. The acaricidal activity of each synthesized derivative against 71etrait},chus urticae was tested and some of the derjvatives showed higher activits, than parent milbemyein A4. Among them, 24a-methylmilbemycin A, (22) was the most active derivatis'e, with l00% momtality ofthe mite at a concentration of 1 ppm and 50% mortality at a concentration of O.1 ppm.
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